Epigenetics and vascular diseases
نویسندگان
چکیده
منابع مشابه
The Interaction between Epigenetics , Muscle and Cardio - Vascular Diseases
The INTERHEART and the INTERSTROKE studies identified a number of modifiable risk factors (smoking, diabetes, dietary patterns, physical activity, etc.) that are associated with the presence of cardiovascular disease (CVD). Recent international studies have shown that lower handgrip (HG) strength is associated with an increased risk of CVD death and total mortality both in initially healthy adu...
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Epigenetics is defined as the study of all inheritable and potentially reversible changes in genome function that do not alter the nucleotide sequence within the DNA. Epigenetic mechanisms such as DNA methylation, histone modification, nucleosome positioning, and microRNAs (miRNAs) are essential to carry out key functions in the regulation of gene expression. Therefore, the epigenetic mechanism...
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For a long time, scientists have tried to describe disorders just by genetic or environmental factors. However, the role of epigenetics in human diseases has been considered from a half of century ago. In the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurod...
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The study of ocular diseases and epigenetic dysregulation is an emerging area of research. The knowledge from the epigenetic mechanisms of DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs regarding the pathogenesis of ocular diseases will be helpful for improved treatment modalities for our patients. In particular, we focus upon the how epigenetic regulatory mec...
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ژورنال
عنوان ژورنال: Journal of Molecular and Cellular Cardiology
سال: 2019
ISSN: 0022-2828
DOI: 10.1016/j.yjmcc.2019.06.010